diabetes.
Conditions
Interventions
Intervention 1: Intervention group 2: Using pioglitazone remedy. Abidi company
pioglitazone 30 mg plus metformin 1500 mg and sulfonylurea 10-20mg per day for 12 weeks. Intervention 2: Intervention gr
Treatment - Drugs
Intervention group 2: Using pioglitazone remedy. Abidi company
pioglitazone 30 mg plus metformin 1500 mg and sulfonylurea 10-20mg per day for 12 weeks
Intervention group 1: Using sitagliptin remedy. Abidi company
sitagliptin 50 mg plus metformin 1500 mg and sulfonylurea 10-20mg per day for 12 weeks
Sponsors
Vice Chancellor for research of Lorestan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with type 2 diabetes who are older than 18 years treated with 1500 mg metformin and 10-20mg sulfonylureas per day are included in the study. These patients should have HbA1c greater than 7 and fasting glucose greater than 126 mg / dL. Exclusion criteria: 1) patients who have type 1 diabetes, 2) known case of heart disease and exertional dyspnea, grade 3 and 4 3) kidney disease (GFR <30), 4) ALT / AST more than 3 times normal
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FPG, HbA1c. Timepoint: Before and three months after intervention. Method of measurement: mg/dl, %. | — |
Secondary
| Measure | Time frame |
|---|---|
| Insulin, HOMA index, weight, HDL, TG, LDL, blood pressure. Timepoint: Before and three months after intervention. Method of measurement: Kg, mg/dl, mg/dl, mg/dl, mmHg. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactForoozan Fathi
Lorestan University of Medical Sciences
Outcome results
None listed