effect of Dexmedetomidine and Neostigmine in ?patients with chronic back pain

Comparison between dexmedetomidine and neostigmine coadministered ?with lidocaine 1.5% and triamcinolone for epidural administration to ?patients with chronic back pain

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016112620258N18

Enrollment

Registered

2016-12-07

Start date

2016-11-05

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic back pain. Low back pain

Interventions

Intervention 1: We injected 1 milligram Neostigmine in N group. Intervention 2: We injected 0.5 microgram in kilogram Dexmedetomidine in D group. Intervention 3: We injected 0.5 milligram Neostigmin

Treatment - Drugs

We injected 1 milligram Neostigmine in N group.

We injected 0.5 microgram in kilogram Dexmedetomidine in D group.

We injected 0.5 milligram Neostigmine and 0.5 microgram in kilogram Dexmedetomidine in ND group .

Eligibility

Sex/Gender

All

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Lumbar epidural block; 30-70 years; ASA I and II; lack of vitamin D Exclusion criteria: Allergy for this drug; failure in epidural block; history of fracture; lack of psychological disorders

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Heart rate. Timepoint: every 5 minutes to recovery. Method of measurement: beat per minute.;Oxygen saturation. Timepoint: every 5 minutes to recovery. Method of measurement: percent.;Mean arterial pressure. Timepoint: every 5 minutes to recovery. Method of measurement: millimeter Hg.;Duration of analgesia. Timepoint: in recovery, one month and three months after block. Method of measurement: minute.;Pain. Timepoint: in recovery, one month and three months after block. Method of measurement: analog visual scale.	—

Measure

Time frame

Heart rate. Timepoint: every 5 minutes to recovery. Method of measurement: beat per minute.;Oxygen saturation. Timepoint: every 5 minutes to recovery. Method of measurement: percent.;Mean arterial pressure. Timepoint: every 5 minutes to recovery. Method of measurement: millimeter Hg.;Duration of analgesia. Timepoint: in recovery, one month and three months after block. Method of measurement: minute.;Pain. Timepoint: in recovery, one month and three months after block. Method of measurement: analog visual scale.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShima Zargar

Arak University Of Medical Sciences

alikamaliir@yahoo.com+98 86 3417 3638

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026