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Comparison of the effect of adding Dexamethasone and Fentanyl to Bupivacaine in transverse abdominal plane block (TAP) on pain intensity after cesarean section by spinal anesthesia in Sari Emam hospital in 1401

Comparison of the effect of adding Dexamethasone and Fentanyl to Bupivacaine in transverse abdominal plane block (TAP) on pain intensity after cesarean section by spinal anesthesia in Sari Emam hospital in 1401

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20161126031095N3
Enrollment
60
Registered
2023-06-21
Start date
2023-06-22
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Other acute postprocedural pain. Other acute postprocedural pain

Interventions

Intervention 1: Intervention group: 50 micrograms of fentanyl plus 17 ml of 0.25% bupivacaine and 2 ml of 0.9% normal saline in a total volume of 20 ml on each side. Intervention 2: Intervention group

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients 18-50 years old Patients undergoing cesarean section under spinal anesthesia Patients with American Society of Anesthesiology (ASA) class I and II anesthesia status (ASA definition = healthy patient without organic, biochemical or mental disease and ASAII = patient with mild systemic disease such as mild asthma - controlled hypertension - disease has no effect on activity not daily - the possibility of affecting anesthesia and surgery) Patients who can perceive and evaluate their pain on a visual analog pain scale. (VAS; scale 0-10) They were eligible to provide written informed consent to enroll in the study Body mass index kg/m2 = 23.9-18.5 Absence of coagulopathy No alcohol or drug addiction

Exclusion criteria

Exclusion criteria: Having chronic pain, or having underlying diseases such as moderate or severe heart, kidney, lung or nerve diseases, significant scoliosis or kyphosis, excessive obesity Taking painkillers before surgery Infection at the injection site History of abdominal surgery or trauma Respiratory tract infection within 2 weeks New York Heart Association Class >II cardiac status and psychiatric disorders that interfere with pain perception and evaluation They had a history of anaphylaxis using bupivacaine Patients who did not tolerate spinal anesthesia well and had to be converted to general anesthesia for cesarean section Individuals who could not provide informed consent or patients who did not wish to participate in the study

Design outcomes

Primary

MeasureTime frame
Postpartum pain intensity. Timepoint: 0/2/4/6/12 and 24/hours after the operation. Method of measurement: Visual Analogue Scale.;Sedation. Timepoint: 0/2/4/6/12 and 24/hours after the operation. Method of measurement: Sedation criteria.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlieh Zamani Kiasari

Mazandaran University of Medical Sciences

aliehzamani@yahoo.com+98 11 3335 5080

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026