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Therapeutic effect of skin allograft in deep second degree burn wounds

Comparison of therapeutic effect of dressing with skin allograft and silver sulfadiazine in deep second degree burn wounds in Zanjan Ayatollah Mousavi hospital, 2016-2017

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016112431074N1
Enrollment
50
Registered
2017-02-13
Start date
2016-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deep second degree burn wounds of limbs and trunk. Burn of second degree of trunk

Interventions

Intervention 1: In control group we used silver sulfadiazine ointment daily after washing the wounds.we consume 20 gram of ointment for each percent of burn wound(each tube is consist of 50 gram of oi
Treatment - Drugs
Treatment - Other
In control group we used silver sulfadiazine ointment daily after washing the wounds.we consume 20 gram of ointment for each percent of burn wound(each tube is consist of 50 gram of ointment).
In intervention group we applied skin allografts produced by ITP company(Iranian tissue products) as a biological bandage.first we sutured the allograft with few simple stiches then with we badage wit

Sponsors

Zanjan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients with thermal deep second degree burn wound who are admitted in our ward, age above 18,with out respiratory burning, with out any comorbidities like addiction. History of DM, renal disease, malignancies, psychiatric problems and non- pregnant patients. Exclusion criteria: head and neck burn wounds; genitalia burn wounds; pregnant patients; third and forth degree burn wounds; unstable patients; patients with burn wounds BSA>20% or BSA<10%; psychiatric patients; addict and smoker patients; patients with other comorbidities like renal and hepatic problem, DM, malnutrition and immunocompromised patients, respiratory burning, old wounds; infected wounds and age below 18.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: Daily during admission. Method of measurement: VAS scale.;Epitelialisation duration. Timepoint: days: 7, 14 and 30. Method of measurement: Physical examination.;Amount of IV pain killer. Timepoint: Daily during admission. Method of measurement: Nursing report.;Finall remaining scar. Timepoint: Day 30 after intervention. Method of measurement: Physical examination and questionare.

Secondary

MeasureTime frame
Addmision days. Timepoint: Time of discharge. Method of measurement: Discharge ward.;Number of bandage refreshment. Timepoint: Daily during admission. Method of measurement: Nursing report and direct checking.;Treatment cost. Timepoint: At the time of discharge. Method of measurement: Finall bill.;Infection. Timepoint: During admission. Method of measurement: Culture from wound.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Farahanchi Baradaran

Zanjan University of Medical Sciences

dr-ali-farahanchi@zums.ac.ir+98 24 3313 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026