Skip to content

Comparison of analgesia with and without the addition of Dex Methomedin to bupivacaine spinal anesthesia for orthopedic surgery using TOTAL KNEE

Comparison of analgesia with and without the addition of Dex Methomedin to bupivacaine spinal anesthesia for orthopedic surgery using TOTAL KNEE

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016112430808N2
Enrollment
128
Registered
2017-02-13
Start date
2015-09-19
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Analgesia after surgery. Acute pain

Interventions

Intervention 1: case group received 2.5 bupivacaine plus0.5 Dax medetomidine. Intervention 2: control group received 12.5 bupivacaine ml plus 2.5 normal saline.
Treatment - Drugs
case group received 2.5 bupivacaine plus0.5 Dax medetomidine
control group received 12.5 bupivacaine ml plus 2.5 normal saline

Sponsors

Vice Chancellor for research of jahrom University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: aged 18 to 45 years old, Class 1 and 2 ASA Exclusion Criteria:A history of cardiovascular disease, asthma, diabetes, kidney or liver disease or any systemic disease.History of narcotics, alcohol, anti-epileptic drugs, antipsychotic, analgesic.Patients who have severe pain during surgery and general anesthesia are forced to use

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain score. Timepoint: in 1,2,6,12,24 hour post operation. Method of measurement: pain assessment ruler.

Secondary

MeasureTime frame
Blood pressure. Timepoint: 1?2?6?12, 24 hours after surgery. Method of measurement: Blood pressure measuring device.;Pulse rate. Timepoint: 1?2?6?12, 24 hours after surgery. Method of measurement: Pulse oximertry.;The Chills, oral dryness, nausea and vomiting. Timepoint: 1?2?6?12, 24 hours after surgery. Method of measurement: use of a questionnaire researcher.;The rate of post-operative pain medication use. Timepoint: 1?2?6?12, 24 hours after surgery. Method of measurement: total dose administered by injection(mg).

Countries

Iran (Islamic Republic of)

Contacts

Public Contactnavid kalani

Jahrom University of Medical Sciences

navidkalani@ymail.com+98 7157414846199

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026