Irreversible Pulpitis. Pulpitis
Conditions
Interventions
Intervention 1: Ibuprofen: 1 capsule of 600 mg, 1 hour before the local anesthetic injection. Intervention 2: placebo: 1 capsule contain 500 mg lactos mono hydrate, 1 hour before the local anesthetic
Treatment - Drugs
Placebo
Ibuprofen: 1 capsule of 600 mg, 1 hour before the local anesthetic injection
Sponsors
Vice Chancellor for Research and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age 18 or more than 18 years, no contraindications to taking either Ibuprofen (history of any allergic reaction to aspirin, NSAIDS, or Lidocaine with Epinephrine, nasal polyp, history of peptic ulcers or GI bleeding, pregnancy and lactation, renal or hepatic disease), no history of GI disorders or ulcer, having no serious systemic disease. Exclusion criteria: no response to cold test, having sensitivity to percussion and palpation, having radiographic changes such as PDL widening, lack of vital pulp in coronal pulp chamber access cavity preparation, teeth with evidence of crack in their crown, having advanced periodontal disease, taking narcotic drugs or analgesic drugs in recent 24 hours before treatment.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response to cold test. Timepoint: Before taking drug, 1 hour after taking drug before anesthetic injection, after local anesthetic injecyion. Method of measurement: Cold spray. | — |
Secondary
| Measure | Time frame |
|---|---|
| In-operative pain. Timepoint: In access cavity preparation and during treatment. Method of measurement: Using Visual Analogue Scale (VAS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Abbas Pardakhti
Vice Chancellor for Research and Technology
Outcome results
None listed