Identifying the effect of dexmedetomidine on the dosage of Bupivacaine in brachial plexus block.

A comparison of the effect of Dexmedetomidine on the onset and duration of sensory block , using different dosages of Bupivacaine in ultrasound guided Brachial Plexus ( Supraclavicular) block for patients undergoing upper limb surgery.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016112331061N1

Enrollment

Registered

2017-01-31

Start date

2017-02-19

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Supraclavicular block- local anesthesia.

Interventions

Intervention 1: Intervention group 2 : Patients candidate for supraclavicular injection, 20 ml of Bupivacaine 0.5% IV + 0.5 mcg/kg/min dexmedetomidine IV. Intervention 2: Control group : Patients cand

Treatment - Drugs

Intervention group 2 : Patients candidate for supraclavicular injection, 20 ml of Bupivacaine 0.5% IV + 0.5 mcg/kg/min dexmedetomidine IV.

Control group : Patients candidate for supraclavicular injection, 30 ml of Bupivacaine 0.5% IV + Placebo Normal Saline IV infusion 0.5mcg/kg/min .

Intervention group 1 : Patients candidate for supraclavicular injection, 30 ml of Bupivacaine 0.5% IV + 0.5 mcg/kg/min dexmedetomidine IV.

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria :ages 20 to 50; BMI below 35;No history of drug reaction;Patients' informed consent Exclusion Criteria : Unsuccessful Block;The operation lasts for more than 180 minutes; Patients refusal; Any complication;Necessity for general anesthesia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Onset of sensory block. Timepoint: During the intervention. Method of measurement: Digital chronometer.;Onset of motor block. Timepoint: During the intervention. Method of measurement: Digital chronometer.;Duration of sensory block. Timepoint: During the intervention. Method of measurement: Digital chronometer.;Duration of motor block. Timepoint: During the intervention. Method of measurement: Digital chronometer.;Dosage of Bupivacaine 0.05%. Timepoint: During the intervention. Method of measurement: milliliters.	—

Measure

Time frame

Onset of sensory block. Timepoint: During the intervention. Method of measurement: Digital chronometer.;Onset of motor block. Timepoint: During the intervention. Method of measurement: Digital chronometer.;Duration of sensory block. Timepoint: During the intervention. Method of measurement: Digital chronometer.;Duration of motor block. Timepoint: During the intervention. Method of measurement: Digital chronometer.;Dosage of Bupivacaine 0.05%. Timepoint: During the intervention. Method of measurement: milliliters.

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Secondary

Measure	Time frame
Mean atrial pressure 1 minute after the block. Timepoint: 1 minute after the block. Method of measurement: Digital non invasive sphygmomanometer.;Mean atrial pressure 3 minute after the block. Timepoint: 3 minute after the block. Method of measurement: Digital non invasive sphygmomanometer.;Mean atrial pressure 5 minute after the block. Timepoint: 5 minute after the block. Method of measurement: Digital non invasive sphygmomanometer.;Pulse rate one minute after the block. Timepoint: 1 minute after the block. Method of measurement: Pulse oximeter.;Pulse ratethree minute after the block. Timepoint: 3 minute after the block. Method of measurement: Pulse oximeter.;Pulse rate five minute after the block. Timepoint: 5 minute after the block. Method of measurement: Pulse oximeter.	—

Measure

Time frame

Mean atrial pressure 1 minute after the block. Timepoint: 1 minute after the block. Method of measurement: Digital non invasive sphygmomanometer.;Mean atrial pressure 3 minute after the block. Timepoint: 3 minute after the block. Method of measurement: Digital non invasive sphygmomanometer.;Mean atrial pressure 5 minute after the block. Timepoint: 5 minute after the block. Method of measurement: Digital non invasive sphygmomanometer.;Pulse rate one minute after the block. Timepoint: 1 minute after the block. Method of measurement: Pulse oximeter.;Pulse ratethree minute after the block. Timepoint: 3 minute after the block. Method of measurement: Pulse oximeter.;Pulse rate five minute after the block. Timepoint: 5 minute after the block. Method of measurement: Pulse oximeter.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazanin Sheibani

Tehran University of Medical Sciences

n-sheibani@student.tums.ac.ir+98 21 6640 4377

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026