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Thyme gel in reducing knee pain due to Arthritis

The effect of Topical Application of Thymus daenensis Celak Extract Gel vs Diclofenac Gel in Knee Osteoarthritis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016112231025N1
Enrollment
120
Registered
2017-01-20
Start date
2017-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoartritis. Arthrosis, unspecified

Interventions

Intervention 1: The first group received placebo gel topically 3 times a day with 200 mg celecoxib capsules for oral use. Intervention 2: The Second group received Thymus daenensis extract gel 5% gel
Treatment - Drugs
The first group received placebo gel topically 3 times a day with 200 mg celecoxib capsules for oral use
The Second group received Thymus daenensis extract gel 5% gel topically 3 times a day with 200 mg celecoxib capsules for oral use
The Third group received diclofenac gel 1% gel topically 3 times a day with 200 mg celecoxib capsules for oral use

Sponsors

Vice chancellor for research of Shahrekord University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 45_75 years old; a definitive diagnosis of osteoarthritis disease with specialist Exclusion criteria: severe diseases such as metabolic disorders and digestive at the same time; severe infection, sensitivity to thyme extract daenensis, pregnancy, lactation, impaired liver function tests; history of fracture or knee surgery; rheumatoid arthritis

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Improving physical Function. Timepoint: Baseline and Six Weeks later. Method of measurement: WOMAC questionnaire.

Secondary

MeasureTime frame
Pain relief. Timepoint: Baseline and Six Weeks later. Method of measurement: VAS questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMorteza Dehghan

Shahrekord University of Medical Scienties

dehghan@skums.ac.ir+98 38 3222 0016

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026