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Clinical trial effect of Intravenous lidocaine with fentanyl for suppression of fentanyl induced cough in children

Comparison of the effect of pretreatment Intravenous lidocaine with fentanyl for suppression of fentanyl induced cough in children

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016112027677N5
Enrollment
99
Registered
2017-01-02
Start date
2015-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Opioid induced cough. Whooping cough, unspecified

Interventions

Intervention 1: Intervention group 1: Fentanyl will be prepared in 5 cc syringes randomly injected. Intervention 2: Intervention group 2: lidocaine will be prepared in 5 cc syringes and after closing
Treatment - Drugs
Placebo
Intervention group 1: Fentanyl will be prepared in 5 cc syringes randomly injected.
Intervention group 2: lidocaine will be prepared in 5 cc syringes and after closing cord randomly injected.

Sponsors

Urmia University of Medical Sciences
Lead Sponsor
Vice Chancellor for research of Urmia University of Medical Sciences
Collaborator

Eligibility

Sex/Gender
All
Age
2 Years to 10 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Anesthesiologists physical status I ,II; aged 2 to10 years old; elective hernioraphy; general anesthesia Exclusion criteria: patients with body weight less than 20% of the ideal body weight; emergency hernioraphy; a history of asthma; chronic obstructive lung diseases; chronic cough; upper respiratory tract infection within 4 weeks of Surgery; children with malformation of the tongue and oropharynx; allergy to the study drugs

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Cough. Timepoint: Within 2 minutes after fentanyl injection. Method of measurement: patient observation.

Secondary

MeasureTime frame
Mean Arterial Blood Pressure. Timepoint: Within 2 minutes after fentanyl injection. Method of measurement: None Invasive Blood Pressure.;Pulse rate. Timepoint: Within 2 minutes after fentanyl injection. Method of measurement: Electrocardiogram.;The percentage of arterial oxygen. Timepoint: Within 2 minutes after fentanyl injection. Method of measurement: Pulse Oximetry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahryar Sane

Vice chancellor for research, Urmia University of Medical Sciences

sane.sh@umsu.ac.ir; shahryarsane@yahoo.com; dr.sh.sane@gmail.com+98 32224777

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 6, 2026