Effect of bupropion tablets compared to sildenafil tablets and Ginseng on sexual function (erectile dysfunction) in men with type 2 diabetes who were referred to endocrinology clinic of Vali Asr Hospital of Zanjan.

Compare the Efficacy of Bupropion tablets with sildenafil tablet and Ginseng in sexual function in men with type 2 diabetes with erectile dysfunction.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016111819554N11

Enrollment

Registered

2016-12-11

Start date

2016-04-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sexual dysfunction. Male erectile dysfunction, unspecified

Interventions

Intervention 1: 20 patients: Bupropion Tab(150mg)for 10 weeks. Intervention 2: 20 patients: Sildenafil Tab(50mg)for 10 weeks. Intervention 3: 20 patients: Ginseng capsule for 10 weeks. Intervention 4:

Treatment - Drugs

Treatment - Other

Placebo

20 patients: Bupropion Tab(150mg)for 10 weeks

20 patients: Sildenafil Tab(50mg)for 10 weeks.

20 patients: Ginseng capsule for 10 weeks

20 patients: placebo for 10 weeks

Eligibility

Sex/Gender

Male

Age

30 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 30-80 years ild; sexual dysfunction from 6 month ago; no relationship problems with partner from 6 month ago; HbA1c less than 10 & FBS less than 200 from 6 month ago; normal serum testosterone and prolactine levels; non-interference in the our drugs with prescription medications; no history of priapism. Exclusion criteria: the anatomical penile dysfunction; history of prostatectomy; sever hematologic & renal &liver dysfunction; Nitrate consumption; coronary artery disease; blood pressure more than 170/100 or less than 90, proliferative retinopathy; autonomic neuropathy; ketoacidosis history in 2 years ago; tachycardia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Erectile dysfunctions. Timepoint: first day and 10 weeks later. Method of measurement: IIEF-5 standard questionnaire.;Serum colestrol level. Timepoint: first day. Method of measurement: laboratory kits (Calorimetry enzimatic).;Serum triglyceride level. Timepoint: first day. Method of measurement: laboratory kits (Calorimetry enzimatic).;Serumfasting blood sugar level. Timepoint: first day. Method of measurement: laboratory kits (Calorimetry enzimatic).;HbA1c. Timepoint: first day. Method of measurement: laboratory kits.;Serum prolactin level. Timepoint: first day. Method of measurement: laboratory kits (elisa).;Serum Testosterone level. Timepoint: first day. Method of measurement: laboratory kits (elisa).	—

Measure

Time frame

Erectile dysfunctions. Timepoint: first day and 10 weeks later. Method of measurement: IIEF-5 standard questionnaire.;Serum colestrol level. Timepoint: first day. Method of measurement: laboratory kits (Calorimetry enzimatic).;Serum triglyceride level. Timepoint: first day. Method of measurement: laboratory kits (Calorimetry enzimatic).;Serumfasting blood sugar level. Timepoint: first day. Method of measurement: laboratory kits (Calorimetry enzimatic).;HbA1c. Timepoint: first day. Method of measurement: laboratory kits.;Serum prolactin level. Timepoint: first day. Method of measurement: laboratory kits (elisa).;Serum Testosterone level. Timepoint: first day. Method of measurement: laboratory kits (elisa).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Maryam Jameshorani

Zanjan University of Medical Sciences

dr.shirinjameshorani@yahoo.com+98 24 3377 0814

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026