weaning from mechanical ventilation. Other specified medical care
Conditions
Interventions
Intervention 1: Control group: Intravenous Midazolam alone at the dose of 0.15 mg/kg/hour in order to keep the Ramsay score between 2 and 3 during the mechanical ventilation. Intervention 2: Intervent
Treatment - Drugs
Control group: Intravenous Midazolam alone at the dose of 0.15 mg/kg/hour in order to keep the Ramsay score between 2 and 3 during the mechanical ventilation.
Intervention group 1: Intravenous fentanyl alone at the dose of 1-3 mcg/kg/hour in order to keep the Ramsay score between 2 and 3 during the mechanical ventilation.
Intervention group 2: this group receives Midazolam at the dose of 0.15 mg/kg/hour and intravenous fentanyl at the dose of 1-3 mcg/kg/hour in order to keep the Ramsay score between 2 and 3 during the
Sponsors
Vice Chancellor for research of Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Months to 15 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: pediatric ICU patients who are under mechanical ventilation who have normal consciousness level. Exclusion criteria: difficult airway management defined as the airway with a structural abnormality including cleft palate and Pierre Robin syndrome; systemic disorders that affect intubation (Mucopolysaccharidosis); Mallampati score over 2; Patients with unstable hemodynamics.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of self extubation. Timepoint: during mechanical ventilation. Method of measurement: report. | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of days under mechanical ventilation. Timepoint: during hospitalization in intensive care unit. Method of measurement: report. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Sajad Razavi
Shahid Beheshti University of medical sciences
Outcome results
None listed