Stroke. Cerebral infarction, unspecified
Conditions
Interventions
Intervention 1: " Intervention group: Tablet Sertraline 100mg Daily ". Intervention 2: " Intervention group: Tablet Nortriptyline 50 mg Daily ".
Treatment - Drugs
" Intervention group: Tablet Sertraline 100mg Daily "
" Intervention group: Tablet Nortriptyline 50 mg Daily "
Sponsors
Vice chancellor for research, Zanjan University Of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Stroke patients aged 50 to 70 years; The first episode of stroke; abcense of depressive symptom at the begining of study; No history of taking antidepressant before stroke; No contraindication for taking Sertraline and Nortriptyline; No history of aphasia Exclusion criteria: Any history of CNS disorder e.g CVT, ALS, MS, Trauma; Any history of drug abuse; Ang contraindication for taking TCA e.g BPH, angle closure glaucoma, cardiovascular problem; Any history of liver and kidney problem
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: Before intervention, 2 months after intervention and 4 months after intervention. Method of measurement: Nottingham Health Profile Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Depression. Timepoint: At the begining of study, after taking drug treatment. Method of measurement: Beck Depression Inventory. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactEshaghian Mohammad M.D.
Department of Psychiatry Zanjan
Outcome results
None listed