vulvovaginal candidiasis. Candidiasis of vulva and vagina
Conditions
Interventions
Intervention 1: curcumin vaginal cream10% , one applicator per day for 1 week. Intervention 2: Clotrimazole vaginal cream1%, one applicator per day for 1 week.
Treatment - Drugs
curcumin vaginal cream10% , one applicator per day for 1 week.
Clotrimazole vaginal cream1%, one applicator per day for 1 week
Sponsors
Vice chancellor for research Ahvaz JundiShapur University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Being married? only sexual partner? Age between 18 -45? Body Mass Index< 30? signs and symptoms of vulvovaginal candidiasis, positive Gram staining smear and culture from vaginal discharge. Exclusion criteria: being pregnancy, lactation and menopausal period; having any vaginal bleeding; recurrent vulvovaginal candidiasis (4 or more vulvovaginal candidiasis in a year); consumption of immunosuppressive drug; women who had used antibiotic for 2 weeks before the study; history of epilepsy, diabetes, heart disease, high blood pressure, thyroid diseases? women who had used other vaginal creams or suppositories for 1 week before the study; women who had used systemic antifungal drugs for 4 weeks before the study; existence of other vaginal infections; consumption of oral contraceptive.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vaginal discharge. Timepoint: Baseline, 4-7 days after treatment. Method of measurement: Clinical Examination, observation, and medical history.;Itching. Timepoint: Baseline, 4-7 days after treatment. Method of measurement: history.;Vulva and vaginal Erythma. Timepoint: Baseline, 4-7 days after treatment. Method of measurement: Clinical Examination.;Vulva and vaginal burning. Timepoint: Baseline, 4-7 days after treatment. Method of measurement: history.;Vaginal discharge culture results. Timepoint: Baseline, 4-7 days after treatment. Method of measurement: vaginal discharge culture.;Compelet remission. Timepoint: 4-7 days after treatment. Method of measurement: Evauation of clinical symptom's remission and negetive result of vaginal discharge culture. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: 4-7 days after treatment. Method of measurement: question of patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Zahra Abbaspoor
Jondishapour University of Medical Sciences
Outcome results
None listed