Anxiety and Depressive. Generalized anxiety disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Underground employees who use artificial light only during the period of their presence No specific disease or chronic physical and mental illness Male Have at least 21 and a maximum of 30 years
Exclusion criteria
Exclusion criteria: Taking medications that could affect serum melatonin levels including Having depression or any other major psychiatric disorders on DSM IV Having significant acute or chronic systemic disorders including type I diabetes mellitus, uncontrolled thyroid disorders, kidney/prostate/bladder problems which cause excessive urination, congestive heart failure, angina pectoris or other major cardiovascular disorders, hepatitis, asthma or severe respiratory allergies, stroke, Parkinson’s disease, Alzheimer’s disease, schizophrenia, epilepsy, oncologic disorders if less than 1 year since end of treatment, or chronic infections Use of hypnotics, melatonin, stimulants, or other medications that may affect melatonin levels (e.g. ß blockers, drugs that affect prostaglandin synthesis, or drugs that activate hepatic melatonin metabolism) and unwillingness or inability to discontinue the occasional use of these medications for at least 4 weeks before beginning of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anxiety. Timepoint: 3 TIMES: Initiation, Middle and End of the study period. Method of measurement: Cattell’s Anxiety Scale Questionnaire (IPAT).;Depression. Timepoint: 3 TIMES: Initiation, Middle and End of the study period. Method of measurement: Minnesota Multiple Personality Inventory (MMPI).;Plasma melatonin hormone. Timepoint: 3 TIMES: Initiation, Middle and End of the study period. Method of measurement: Blood examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Bagheiat-allah University of Medical Sciences