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The effect of oral N-acetylcysteine on quantitative serum high sensitivity CRP and hemoglobin in hemodialysis patients

Evaluation the effect of oral N-acetylcysteine on quantitative serum high sensitivity CRP and hemoglobin in end stage renal disease patients under hemodialysis

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016111030821N1
Enrollment
40
Registered
2017-03-16
Start date
2016-10-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End stage renal disease. End stage kidney disease

Interventions

Intervention 1: Intervention group: N-acetylcysteine tab, 600 mg bid for 1 month period. Intervention 2: Control group: placebo tab bid, for 1 month period.
Treatment - Drugs
Intervention group: N-acetylcysteine tab, 600 mg bid for 1 month period
Control group: placebo tab bid, for 1 month period

Sponsors

Vice Chancellor for research of Ardabil University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients with positive CRP who were dialyzed at least three times per week for three months Exclusion criteria: Patients with chronic inflammatory diseases such as rheumatoid arthritis and lupus, patients who take HRT drugs during menopause ,patients with malignant blood diseases such as myelodysplastic syndrome, lymphoma, leukemia, bone marrow aplasia and patients with HIV

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
CRP. Timepoint: Before the intervention and one month after intervention. Method of measurement: ELIZA.

Secondary

MeasureTime frame
Hemoglobin. Timepoint: Before the intervention and one month after intervention. Method of measurement: CBC.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRoya Alaei

Ardabil University of Medical Sciences

r.alaei@arums.ac.ir+98 45 3352 2248

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026