metabolic syndrome. lipoprotein metabolic disorder
Conditions
Interventions
Intervention 1: Vitamin C group: who was take only 500 mg/day vitamin C supplements [Morning Time]. Intervention 2: Vitamin C plus physical activity group either morning 7:30 A.M and afternoon after 3
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 50 Years
Inclusion criteria
Inclusion criteria: Participants having MetS, according to IDF definition waist circumference = 94 cm for men and = 80 cm for women (triglyceride level = 150 mg/dl), (high density lipoprotein < 40 mg/dl in male and < 50 mg/dl in female), (raised systolic blood pressure =130 or diastolic blood pressure = 85 mm Hg), (raised fasting plasma glucose =100 mg/dl), age between 30 and 50 years, both male and female, living in Halabja at least 3 years.
Exclusion criteria
Exclusion criteria: If the study participants use medications that might affect blood pressure, plasma glucose and lipid profiles throughout the study, they were excluded. The use of any other supplements containing vitamin D and C was also being the exclusion criteria. Getting pregnant at the middle of the study and lack of use the supplements for average 10 days, was excluded. For physical activity, if the participants are not follow to recommended time and less than 25 mints, they were being excluded. Individuals with type I and type II diabetes who are taking oral hypoglycemic agents or injecting insulin, or any medical therapy affecting the result, smoker [Light smokers include low-rate daily smokers (40 g/day; and long-term institutionalization or residing in nursing homes, pregnancy or lactation as well as post-menopausal women and women with surgical menopause was not to be included. Patients with a history of bariatric surgery and use of weight-loss medications was also not be included. those with high triglyceride level > 400 mg/dl, higher systolic blood pressure level >140 and diastolic blood pressure > 90, and finally raised fasting plasma glucose >125 mg/dl was not included.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum level of vitamin D. Timepoint: at the begining of the study and 3 month after intervention. Method of measurement: ng/ml - specific kits.;Serum level of vitamin C. Timepoint: at the begining of the study and 3 month after intervention. Method of measurement: HPLC - mg/dL.;Systolic blood pressure. Timepoint: at the begining of the study and 3 month after intervention. Method of measurement: Mercury Sphygmomanometerwith the accuracy of 1 mmgh.;Diastolic blood pressure. Timepoint: at the begining of the study and 3 month after intervention. Method of measurement: Mercury Sphygmomanometerwith the accuracy of 1 mmgh.;High-density Lipoprotein. Timepoint: at the begining of the study and 3 month after intervention. Method of measurement: mg/dL - was measured after precipitation of the apolipoprotein B containing lipoproteins with phosphotungistic acid.;Low-density lipoprotein. Timepoint: at the begining of the study and 3 month after intervention. Method of measurement: mg/dL - enzymatic – photometric.;Triglyceride. Timepoint: at the begining of the study and 3 month after intervention. Method of measurement: mg/dL -using triglyceride kits by enzymatic colorimetric tests with glycerol phosphate oxidase.;Fasting plasma glucose. Timepoint: at the begining of the study and 3 month after intervention. Method of measurement: enzymatic colorimetric method using glucose oxidase. | — |
Secondary
| Measure | Time frame |
|---|---|
| Body mass index. Timepoint: before treatment and 3 months following end of treatment. Method of measurement: weight / (height)2 - kg/m2.;Waist circumference. Timepoint: before treatment and 3 months following end of treatment. Method of measurement: cm – tapeline.;Parathyroid hormone. Timepoint: before treatment and 3 months following end of treatment. Method of measurement: Elisa.;Calcium. Timepoint: before treatment and 3 months following end of treatment. Method of measurement: chemical analyzers instrument. | — |
Countries
Iraq
Contacts
Public ContactHalgord Ali M.Farag
Tehran University of Medical Sciences
Outcome results
None listed