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Effect of laser therapy in patients with osteoarthritis of the knee

The effect of low power laser therapy on serum levels of CRP, clinical symptoms and functional performance of patients with knee osteoarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016110830792N1
Enrollment
40
Registered
2016-12-10
Start date
2016-11-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee Osteoarthritis. Gonarthrosis [arthrosis of knee]

Interventions

Intervention 1: Intervention group: Treatments will be include routine physical therapy plus exercise therapy and low level laser therapy. Routine physical therapy consist of:1 MHz continuous mode Ul
Rehabilitation
Intervention group: Treatments will be include routine physical therapy plus exercise therapy and low level laser therapy. Routine physical therapy consist of:1 MHz continuous mode Ultrasound, durat
Control group: Treatments will be include routine physical therapy plus exercise therapy and placebo laser therapy. Routine physical therapy consist of:1 MHz continuous mode Ultrasound, duration of

Sponsors

University of Social Welfare and Rehabilitation Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: According to the criteria of the American College for Rheumatology; participants with knee osteoarthritis at the levels 2–4 according to Kellgren–Lawrence grade; have knee pain and functional disability for at least three months; age between 40 and 60 years; both genders; acute and chronic Osteoarthritis; at least three months have passed since the last Physiotherapy; pain intensity = 3 on a 10 cm Visual Analogue Scale (VAS) Exclusion criteria: use continuous anti-inflammatory drugs during the experiment; having symptomatic hip osteoarthritis; having any disease where laser treatment is contraindicated (cancer and diabetes); history of Knee surgery and trauma to the knees; neurological disorder; Rheumatologic and other inflammatory diseases; Liver disease

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
C_reactive protein. Timepoint: Before intervention and post-intervention and after two weeks follow up. Method of measurement: ELISA method.;Pain at rest and activity. Timepoint: Before intervention and post-intervention and after two weeks follow up. Method of measurement: visual analog scale.;Pain. Timepoint: Before intervention and post-intervention and after two weeks follow up. Method of measurement: WOMAC questionnaire.;Pain. Timepoint: Before intervention and post-intervention and after two weeks follow up. Method of measurement: KOOS questionnaire.;Knee range of motion in flexion and extension. Timepoint: Before intervention and post-intervention and after two weeks follow up. Method of measurement: by goniometer.

Secondary

MeasureTime frame
Improved function. Timepoint: Before intervention and post-intervention and after two weeks follow up. Method of measurement: KOOS questionnaire.;Improved function. Timepoint: Before intervention and post-intervention and after two weeks follow up. Method of measurement: Time up and go test.;Improved function. Timepoint: Before intervention and post-intervention and after two weeks follow up. Method of measurement: WOMAC questionnaire.;Maximum quadriceps muscle strength. Timepoint: Before intervention and post-intervention and after two weeks follow up. Method of measurement: digital analayzer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactForouzan Rastgar Koutenaei

University of Social Welfare and Rehabilitation Sciences

forooz.pt@gmail.com+98 21 4424 1361

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026