The effect of therapeutic foot bath with chamomile and peppermint on restless legs syndrome

Effects of Therapeutic Foot Bath with Chamomile (Anthemis pseudocotul Boiss.) and Peppermint (Mentha piperita) on the Severity of Restless Legs Syndrome, Sleep Quality, and Quality of Life in Patients with Multiple Sclerosis Attending the MS Clinic at Shafa Hospital in Kerman: A Randomized Controlled Trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20161108030776N6

Enrollment

Registered

2025-11-25

Start date

2025-11-22

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Restless legs syndrome. Polyneuropathy in diseases classified elsewhere

Interventions

Intervention 1: Intervention group: Intervention group: Patients who will receive a therapeutic bath with a combination of chamomile and peppermint herbs. In the intervention group, the treatment will

Eligibility

Sex/Gender

All

Age

20 Years to No maximum

Inclusion criteria

Inclusion criteria: Co-occurrence of multiple sclerosis and restless legs syndrome

Exclusion criteria

Exclusion criteria: Having any chronic neurological, psychological, or metabolic disease Pregnancy or breastfeeding

Design outcomes

Primary

Measure	Time frame
Severity of restless legs syndrome. Timepoint: At the beginning of the study and 4 weeks later. Method of measurement: Restless Legs Syndrome Rating Scale (RLSRS) questionnaire.;Sleep quality. Timepoint: At the beginning of the study and 4 weeks later. Method of measurement: Pittsburgh Sleep Quality Index (PSQI) questionnaire.;Quality of life. Timepoint: At the beginning of the study and 4 weeks later. Method of measurement: Multiple Sclerosis Quality of Life (MSQOL-54) questionnaire.	—

Measure

Time frame

Severity of restless legs syndrome. Timepoint: At the beginning of the study and 4 weeks later. Method of measurement: Restless Legs Syndrome Rating Scale (RLSRS) questionnaire.;Sleep quality. Timepoint: At the beginning of the study and 4 weeks later. Method of measurement: Pittsburgh Sleep Quality Index (PSQI) questionnaire.;Quality of life. Timepoint: At the beginning of the study and 4 weeks later. Method of measurement: Multiple Sclerosis Quality of Life (MSQOL-54) questionnaire.

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Secondary

Measure	Time frame
Any possible side effects. Timepoint: During the use of herbal medicine. Method of measurement: Questioning the patient.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohadese Kamali

Kerman University of Medical Sciences

mohadesekamali0912@gmail.com+98 34 3133 6000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026