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The effect of Centella asiatica L. on cognitive disorders in MS

The effect of Centella asiatica L. on cognitive impairments in patients with multiple sclerosis (MS)

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20161108030776N5
Enrollment
96
Registered
2024-06-15
Start date
2022-08-06
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis (MS). Demyelinating diseases of the central nervous system

Interventions

Intervention 1: Intervention group: Every 12 hours after meals, they received a capsule containing Centella asiatica plant powder for two months. Intervention 2: Control group: Every 12 hours after me

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Multiple sclerosis patients with complaints of cognitive impairment referred to the MS clinic and had proven cognitive impairment based on the BICAMS (brief international cognitive assessment for MS) test.

Exclusion criteria

Exclusion criteria: Suffering from psychiatric diseases such as severe depression, schizophrenia, etc. pregnancy breastfeeding

Design outcomes

Primary

MeasureTime frame
Severity of cognitive impairment. Timepoint: Investigation of cognitive impairment at the beginning of the study (before the start of the intervention) and two months after the start of the intervention with the Centella asiatica. Method of measurement: BICAMS questionnaire.;Quality of Life. Timepoint: At the beginning of the study (before the start of the intervention) and two months after the start of Centella Asiatica. Method of measurement: MSQOL54 questionnaire.

Secondary

MeasureTime frame
Possible side effects. Timepoint: At the end of the study. Method of measurement: Registration by the patient and questions from the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohadese Kamali

Kerman University of Medical Sciences

mohadesekamali0912@gmail.com+98 34 3133 6000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026