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Effects of Zinc in the treatment of patients with pulmonary tuberculosis

Effects of Zinc as a supplemental therapy in the treatment of patients with pulmonary tuberculosis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016110630729N1
Enrollment
90
Registered
2016-12-26
Start date
2016-03-19
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary tuberculosis. Respiratory tuberculosis, bacteriologically and histologically confirmed

Interventions

Intervention 1: Treatment intervention will be conducted by using zinc sulfate syrup (250 mg dosage) (Iran Daroo company) which will be taken once a day (after dinner) for six months. Intervention 2:
Treatment - Drugs
Placebo
Treatment intervention will be conducted by using zinc sulfate syrup (250 mg dosage) (Iran Daroo company) which will be taken once a day (after dinner) for six months
and intervention with placebo will be conducted with placebo assumption once a day (after dinner) for six months.

Sponsors

Zabol University of Medical Sciences and Health Services
Lead Sponsor

Eligibility

Sex/Gender
All
Age
10 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: All tuberculosis diagnosed patients with the age ranged between 10-60 years. Exclusion criteria: Any chromosomal disorders; allergy to zinc; chronic renal disease; any other supplement or placebo assumption; side effect appearance such as blurred vision, pulmonary edema, icter and severe gastrointestinal symptoms.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sputum smear. Timepoint: Beginning of diagnosis and two months, four months and six months after diagnosis. Method of measurement: Sputum smear.

Secondary

MeasureTime frame
Serum zinc level. Timepoint: Beginning of diagnosis and two months, four months and six months after diagnosis. Method of measurement: Serum zinc level in micrograms per liter.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDonya Arefi

Zabol University of Medical Sciences

donya.arefi@gmail.com+98 54 3223 0770

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026