Condition 1: Migraine headaches. Condition 2: Migraine headaches. Migraine without aura (common migraine Migraine with aura (classic migraine)
Conditions
Interventions
Intervention 1: patients in this group take Citalopram thirty milligrams at noon for two months. Dose escalation is gradually within two weeks. Intervention 2: Cotrol group: Patients take placebo whic
Sponsors
Shahed University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Age between 18 to 45. Suffering from migraine headaches according to international headache society criteria(IHS). At least three attack of migraine in one month. History of migraine for at least six months.
Exclusion criteria
Exclusion criteria: Suffering from another type of headaches such as Cluster,Tension,.... . History of Asthma, Renal and Heart failure, Depression, any allergic reaction to drugs used in study or similar drugs. Patients who already take drugs for treatment for migraine. History of using anti depressant, anti epileptics, Analgesics, Corticosteroids, Opium, Monoamine Oxidase, and Non steroidal anti inflammatory agents for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Headache Intensity. Timepoint: At the beginning and at the end of first and second month. Method of measurement: Visual Analougue Scale, And Six points behavioral rating scale BRS-6.;Headache frequency. Timepoint: At the beginning and at the end of second month. Method of measurement: Number of attacks in one month.;Headache duration. Timepoint: At the beginning and at the end of second month. Method of measurement: Average of headaches duration in hour. | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug reactions such as skin redness, pruritus, burning sensation,. Timepoint: Immediately after patient alarm. Method of measurement: Observation and consultation with proper specialist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSiamak Afshinmajd
Shahed University
Outcome results
None listed