Irritable bowel syndrom. Irritable bowel syndrome with diarrhea, Irritable bowel syndrome without diarrhoea
Conditions
Interventions
Intervention 1: Tow capsule (each capsule contain 250mg achillea wilhelmsii ) daily for a month in test group. Intervention 2: Tow capsule (each capsule contain 250mg HPMC )daily for a month in plac
Treatment - Drugs
Placebo
Tow capsule (each capsule contain 250mg achillea wilhelmsii ) daily for a month in test group.
Tow capsule (each capsule contain 250mg HPMC )daily for a month in placebo group.
Sponsors
Vice – Chancellery of Research, Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria : age>18 ; ability to swallow the capsule ; patients who sign the testimonials and cooperate during the study ; patients who are not cured with Achillea wilhelmsii during a last month ; Patients who their diseases are approved by complete medical evaluation. Exclusion criteria : pregnant patients and nursing mothers ; patients with any active stomach-interic disease ; patients who have to use other drugs that interference with this medication (such as laxative? antidepressants? opioid and narcotic analgesics ) ; patients who are disposed to a serious health danger, such as severe cardiac, liver or renal diseases ; If significant side effects occur, the patient will be excluded from the study ; patients with severe allergy to this plant (dermatitis contact) will be excluded.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diarrhea. Timepoint: Before using the drug-2 weeks after using the drug-30 days after using the drugs. Method of measurement: Based on IBS-QOL and IBS-SEVERITY questionary.;Constipation. Timepoint: Before using the drug-2 weeks after using the drug-30 days after using the drugs. Method of measurement: Based on IBS-QOL and IBS-SEVERITY questionary.;Bloat. Timepoint: Before using the drug-2 weeks after using the drug-30 days after using the drugs. Method of measurement: Based on IBS-QOL and IBS-SEVERITY questionary.;Abdominal pain. Timepoint: Before using the drug-2 weeks after using the drug-30 days after using the drugs. Method of measurement: Based on IBS-QOL and IBS-SEVERITY questionary. | — |
Secondary
| Measure | Time frame |
|---|---|
| Photosensivity. Timepoint: Before start use drug-two weeks after use drug-four weeks after use drug. Method of measurement: Based on side effect questionary.;Digestive problems. Timepoint: Before start use drug-two weeks after use drug-four weeks after use drug. Method of measurement: Based on side effect questionary. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSayede Padide Derakhshande
Faculty of pharmacy, Kermanshah University of Medical Sciences
Outcome results
None listed