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Luteal phase support during frozen embryo transfer cycle

Duration of estrogen for luteal phase in pregnant women undergone frozen embryo transfer cycles- Randomized controlled trials Phase III

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201611011141N24
Enrollment
100
Registered
2017-02-01
Start date
2016-05-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility, unspecified. Female infertility, unspecified

Interventions

Intervention 1: Discontinued of estrogen in luteal phase support in 6 week of pregnancy and fetal heart beat. Intervention 2: No intervention.
Treatment - Drugs
Discontinued of estrogen in luteal phase support in 6 week of pregnancy and fetal heart beat
No intervention

Sponsors

Royan institute, Vice chancellor for research
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
21 Years to 37 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with surplus embryos undergone infertility treatment cycles (e.g. OHSS, inadequate endometrium, surplus frozen embryo from any cause); Age 21-37 years; Normal BMI (18.5 <BMI <30); IVF / ICSI or IVF or ICSI cycles with antagonists or agonists protocols; Frozen embryos on 2-3 days. Exclusion criteria: Endometrial thickness =7mm; Egg Donors; Surrogacy; Male factor infertility with azoospermia; Age <37 years old; Hydrosalpinx; Uterine anomalies; Myoma with a compression effect or submocusa myoma; PGD; Blastocyst embryo transfer, ZIFT and GIFT.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Ongoing pregnancy rate. Timepoint: 6 & 12 weeks of pregnancy. Method of measurement: ultrasonography.

Secondary

MeasureTime frame
Estrogen. Timepoint: start using progesterone for luteal support in FET cycle (day 15), the day of embryo transfer, 6 and 12 weeks of pregnancy. Method of measurement: Blood serum level.;Progesterone. Timepoint: start using progesterone for luteal support in FET cycle (day 15), the day of embryo transfer, 6 and 12 weeks of pregnancy. Method of measurement: Blood serum level.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Abdolhoseyn Shahverdi

Royan Institute

shahverd2002@yahoo.com+98 21 2230 6481

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026