The effects of a salt substitute on an Iranian population.

The effects of a reduced-sodium, high-potassium salt substitute on hypertensive and normal population of Baharlou Clinic clients, Tehran, Iran at 2016-2017

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016103130572N1

Enrollment

250

Registered

2016-12-08

Start date

2016-12-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension. Essential (primary) hypertension

Interventions

Intervention 1: Intervention Group: Low sodium salt (80 percent sodium Chloride and 20 percent Potassium Chloride) for 3 months as the exclusive salt consumed. Intervention 2: Control Group: Regular S

Prevention

Placebo

Intervention Group: Low sodium salt (80 percent sodium Chloride and 20 percent Potassium Chloride) for 3 months as the exclusive salt consumed

Control Group: Regular Salt (100 percent sodium chloride) for 3 month as the exclusive salt consumed

Eligibility

Sex/Gender

All

Age

25 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Age 25-65; Blood Pressure equal to or greater than 140 Systolic or 90 Diastolic in three measurements in two settings or consuming an anti-hypertensive drug; Cooperative with consuming salt for 3 months Exclusion Criteria: Abnormal Serum Creatinine; Abnormal Serum Urea; Consuming medications: Digoxin, Lithium, K-Sparing Diuretics; Acute or Severe Cardiovascular Disease; Psychotic Disorders; Eating fast-foods or take-away foods or going to restaurant more than once a week

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Systolic Blood Pressure. Timepoint: First Day, End of Month1, End of Month2, End of Month3. Method of measurement: digital blood pressure monitor (3 measurements in each visit).;Diastolic Blood Pressure. Timepoint: First Day, End of Month1, End of Month2, End of Month3. Method of measurement: digital blood pressure monitor (3 measurements in each visit).;Sodium in 24 hour Urine collected. Timepoint: At first day and last day of the study. Method of measurement: 24-h urine collection.;Potassium in 24 hour urine collection. Timepoint: At first day and last day of the study. Method of measurement: 24-h urine collection.	—

Measure

Time frame

Systolic Blood Pressure. Timepoint: First Day, End of Month1, End of Month2, End of Month3. Method of measurement: digital blood pressure monitor (3 measurements in each visit).;Diastolic Blood Pressure. Timepoint: First Day, End of Month1, End of Month2, End of Month3. Method of measurement: digital blood pressure monitor (3 measurements in each visit).;Sodium in 24 hour Urine collected. Timepoint: At first day and last day of the study. Method of measurement: 24-h urine collection.;Potassium in 24 hour urine collection. Timepoint: At first day and last day of the study. Method of measurement: 24-h urine collection.

—

Secondary

Measure	Time frame
Attrition rate due to unacceptable salt taste. Timepoint: End of the study. Method of measurement: Attrition rate due to unacceptable salt taste in intervention group compared to control group.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Mohammadi

Community Medicine Department, TUMS

dr.m.mohamadii@gmail.com, mohammadi.mo@razi.tums.ac.ir+98 21 8896 2357

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026