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Comparing the effect of oxytocin alone versus oxytocin plus intravenous and oral propranolol on labor progression

Comparing the effect of oxytocin alone versus oxytocin plus intravenous and oral propranolol on labor progression

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016103012789N13
Enrollment
123
Registered
2016-12-04
Start date
2016-04-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Induction and Promotion of labor. Spontaneous vertex deliveryr

Interventions

Intervention 1: Intervention group oxytocin alone with dose 2 mIU/min which increase every 15 min. Intervention 2: Intervention group oxytocin plus intravenous propranolol, oxytocin with dose 2 mIU/mi
Treatment - Drugs
Intervention group oxytocin alone with dose 2 mIU/min which increase every 15 min
Intervention group oxytocin plus intravenous propranolol, oxytocin with dose 2 mIU/min which increase every 15 min and propranolol 2 mg/ml IV
Intervention group oxytocin plus oral propranolol, oxytocin with dose 2 mIU/min which increase every 15 min and propranolol 20 mg oraly

Sponsors

Vice Chancellor for Research of Kurdistan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Nulliparity, singleton, cephalic presentation, fetal heart rate between 120 to 160 beats per minute, approximate weight of 2,500 to 4,000 (by examination or ultrasound), the maternal heart rate between 60 to 130 beats per minutes. Exclusion Criteria: CPD, any history of previous surgery on the uterus, fetal distress, the risk of macrosomia or polyhydramnius, SBP=100, PR=60, PR=130 min, any history of cardiopulmonary disease, metabolic disease of mother or taking medicine for any illness by mother.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The duration of phases of labor. Timepoint: From the intervention to delivery. Method of measurement: vaginal exam.

Secondary

MeasureTime frame
Pregnancy ending in caesarean section. Timepoint: After the second period of injection. Method of measurement: Based on the indications for cesarean section.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Narjes Marjani

Kurdistan University of Medical Sciences

melica313@yahoo.com+98 87 3328 8119

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026