Diabetes. Insulin-dependent diabetes mellitus
Conditions
Interventions
Intervention 1: In case group, severity of dehydration estimates in patient with mild and mod DKA and treat.After second hour of treatment ,aspart insulin(0/1 iu/kg) use, subcutaneous every 2 hours u
Treatment - Drugs
In case group, severity of dehydration estimates in patient with mild and mod DKA and treat.After second hour of treatment ,aspart insulin(0/1 iu/kg) use, subcutaneous every 2 hours until DKA has res
In control group, patients treat with regular insulin, 0/1 iu/kg, intravenous, infusion and continued until DKA has resolved
Sponsors
Hamedan University Of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Years to 17 Years
Inclusion criteria
Inclusion criteria: inclusion criteria: blood sugar>300mg/d ; PH < 3.7; urine keton +2 or more with dipstick or in urine analysis ; history of polydipsia, Frequency, Enuresis, weight loss exclusion criteria: DKA caused by infections in patients;patients with epilepsy or underline disease;patients with endocrine disorders;patients with inborn error of metabolism patients with metabolic acidosis that treated with intravenous bicarbonate in an other center; patients that PH and dehydration's become worse
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ABG. Timepoint: Every 4 hours. Method of measurement: Peripheral blood samples.;The number of hospitalization. Timepoint: end of study. Method of measurement: The number.;ICU admission. Timepoint: end of study. Method of measurement: The number.;Sign of brain edema. Timepoint: daily. Method of measurement: Clinical.;Electrolysis imbalance. Timepoint: Every 4 hours. Method of measurement: Peripheral blood samples.;Response time to treatment. Timepoint: Every 2 hours. Method of measurement: blood sugar with glucometer and ABG.;Hpoglycemia. Timepoint: Every 2 hours. Method of measurement: blood sugar with glucometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hypoglycemia. Timepoint: every 2 hours. Method of measurement: blood sugar with glucometer.;Electrolysis imbalance. Timepoint: every 4 hours. Method of measurement: Peripheral blood samples.;Sign of brain edema. Timepoint: every 2 hours. Method of measurement: clinical. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Saba Maher
Hamedan University Of Medical Sciences
Outcome results
None listed