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Reduction of opioid use by co therapy with iv acetaminophen

Comparison of opioids use reduction with IV acetaminophen in patients underwent spine CD implantation surgeries who use PCA method

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016102930564N1
Enrollment
86
Registered
2016-12-13
Start date
2016-11-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Vertebral CD implantation. Condition 2: CD implantation in vertebral surgery. Vertebral fractures Vertebral fractures

Interventions

Intervention 1: intervention group 1 gr acetaminophen after induction of anesthesia and then every 6 hours for 24 hours. Intervention 2: For group placebo 100cc salin in microcet after anesthesia and
Treatment - Drugs
Placebo
intervention group 1 gr acetaminophen after induction of anesthesia and then every 6 hours for 24 hours.
For group placebo 100cc salin in microcet after anesthesia and then every 6 hours for 24 hours will be infused.

Sponsors

Ardabil University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients aged 20 to 70 years old; ASA 1,2 after obtaining informed consent will be enrolled. Patient with renal disease, liver disease, uncontrolled hypertension, GI bleeding, platelet disorders, sensitivity to NSAIDS, drug abuse, alcohol abuse, and psychotropic drug users, are excluded.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain relief. Timepoint: Every 6 hours. Method of measurement: Pain assesssment based on visual analogus scale.

Secondary

MeasureTime frame
Reduce of nausea and vometing,. Timepoint: 6 houres. Method of measurement: clinical.;Reduce of constipation. Timepoint: every 6 houres. Method of measurement: clinical.;Reduce of drowsiness. Timepoint: every 6 houres. Method of measurement: ramsey score.;Reduce of anaphylaxis. Timepoint: every 6 houres. Method of measurement: clinical.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Safy

Ardabil Fatemi hospital

msafi8681@gmail.com+98 45 3323 2520

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026