The effect of ibuprofen on the pain during pulp therapy of mandibular primary molars

The effect of ibuprofen premedication on the success of inferior alveolar nerve block anesthesia for primary molars with irreversible pulpitis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20161029030552N3

Enrollment

Registered

2019-03-04

Start date

2017-08-23

Completion date

Unknown

Last updated

2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irreversible pulpitis. K04.0

Interventions

Intervention 1: Intervention group: prescribing Ibuprofen (10 mg/kg) prior to treatment. Intervention 2: Control group: prescribing placebo prior to treatment.

Eligibility

Sex/Gender

All

Age

6 Years to 10 Years

Inclusion criteria

Inclusion criteria: Healthy patients having a carious mandibular primary molar with symptomatic irreversible pulpitis Spontaneous pain of the mentioned tooth Absence of radiolucency in the furcation area

Exclusion criteria

Exclusion criteria: Consumption of NSAIDs or other analgesics in the previous 12 hours Allergy to NSAIDs History of GI disturbances Presence of necrotic pulp tissue after access cavity preparation

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: During pulp exposure. Method of measurement: Visual analogue scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactYasamin Khaksar

Shiraz University of Medical Sciences

khaksar_y@sums.ac.ir+98 71 3626 3193

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026