Ulcerative Colitis. Ulcerative colitis
Conditions
Interventions
Intervention 1: Intervention group: Addition of 20 miligram atorvastatin/daily for 6 months to routine treatment regime including asacol, azathioprine and hydrocortisone. Intervention 2: Control group
Treatment - Drugs
Intervention group: Addition of 20 miligram atorvastatin/daily for 6 months to routine treatment regime including asacol, azathioprine and hydrocortisone
Control group: Addition of 20 miligram plasebo/daily for 6 months to routine treatment regime including asacol, azathioprine and hydrocortisone
Sponsors
Vice chancellor for research, Zahedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Main inclusion criteria: developing ulcerative colitis with pathologic confirmation; patients at the age of 18-60 years old. Main exclusion criteria: not taking medication as directed by doctor; drug allergy or severe drug side effects; cancer; history of surgery on the gastrointestinal tract; malabsorption disease; vasculitis disease.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of remission. Timepoint: Every 3 months since study start. Method of measurement: Day.;Frequency of flare. Timepoint: Every 3 months since study start. Method of measurement: Number.;The need for steroids. Timepoint: Every 3 months since study start. Method of measurement: Miligram per kilogram.;Number of hospitalization. Timepoint: Every 3 months since study start. Method of measurement: Number. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLeila Hosseini
Zahedan University of Medical Sciences
Outcome results
None listed