Efficacy of Dexmedetomidine and Ketamin in Epidural ? Anesthesia to Bupivacaine %0.25 to reduce postoperative Analgesia in fracture ?femur.?

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016102620258N16

Enrollment

105

Registered

2016-11-15

Start date

2016-10-07

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Femur fracture. Fracture of neck of femur

Interventions

Intervention 1: We injected 0/5 geram Dexmedetomidine (30-35 geram) in first ?group . Intervention 2: We injected 25 ?milligram Ketamin ( 0/5 milliliter) in second group.?. Intervention 3: We injected

Treatment - Drugs

We injected 0/5 geram Dexmedetomidine (30-35 geram) in first ?group .

We injected 25 ?milligram Ketamin ( 0/5 milliliter) in second group.?

We injected ?0/5 ?milliliter normal saline (0/5 milliliter) in control group.

Eligibility

Sex/Gender

All

Age

40 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 40-85 years; ASA I and II; lack of sensitivity to drugs; lack of substance abuse; lack of epidural contraindications; duration of surgery 90-120 minute. Exclusion criteria: body mass index 35 and more; need to general anesthesia; duration surgery more than 120 minute; other fracture; chronic disease.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Heart rate. Timepoint: Every 5 minute to 15 minute and every 15 minute to 1 hour in surgery? and in recovery. Method of measurement: Count in minute.;Respiratory rate. Timepoint: Every 5 minute to 15 minute and every 15 minute to 1 hour in surgery?. Method of measurement: Count in minute.;Blood pressure. Timepoint: Every 5 minute to 15 minute and every 15 minute to 1 hour in surgery? and in recovery. Method of measurement: Sphygomanometer.;Pain. Timepoint: At recovery room and 4 and 12 and 24 hours after surgery. Method of measurement: Visual Analogue Scale.;Mean of narcotic needed. Timepoint: 24 hour after surgery. Method of measurement: milligram.	—

Measure

Time frame

Heart rate. Timepoint: Every 5 minute to 15 minute and every 15 minute to 1 hour in surgery? and in recovery. Method of measurement: Count in minute.;Respiratory rate. Timepoint: Every 5 minute to 15 minute and every 15 minute to 1 hour in surgery?. Method of measurement: Count in minute.;Blood pressure. Timepoint: Every 5 minute to 15 minute and every 15 minute to 1 hour in surgery? and in recovery. Method of measurement: Sphygomanometer.;Pain. Timepoint: At recovery room and 4 and 12 and 24 hours after surgery. Method of measurement: Visual Analogue Scale.;Mean of narcotic needed. Timepoint: 24 hour after surgery. Method of measurement: milligram.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Taraneh Radbin

Faculty of Medicine

radbin@yahoo.com+98 86 3471 3645

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026