ASC-H. •Atypical squamous cells on cervical Papanicolaou smear cannot exclude high grade squamous intraepithelial lesion
Conditions
Interventions
Intervention 1: In intervention group Doxycycline cap 100 mg PO bid given for 5 days
and honey gel 10% 10 cc vaginally given for a week. Intervention 2: In control group Doxycycline cap 100 mg PO bid given for 5 days
and placebo gel 10 cc given for a week.
Treatment - Drugs
Placebo
In intervention group Doxycycline cap 100 mg PO bid given for 5 days
and honey gel 10% 10 cc vaginally given for a week.
In control group Doxycycline cap 100 mg PO bid given for 5 days
Sponsors
Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: All patients referred for evaluation by colposcopy due to ASC-H in pap smar
Exclusion criteria
Exclusion criteria: Any immune deficiency; cigarette smoking; any chronic disease that interfere with wound healing such as DM; medication usage that interfere with wound healing: corticosteroids; anticoagulants immunosuppressant and chemotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Healing of erosions caused by colposcopy. Timepoint: One and two weeks after treatment. Method of measurement: In weekly visits of patients; erosions are evaluated and the healing staging is done with qualitative measures: totally repaired; partially repaired; no change. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluating erosion healing in case and control group. Timepoint: One and two weeks after treatment. Method of measurement: in 3 qualitative groups: totally repaired; partially repaired; no change.;Evaluating cervical colposcopic status. Timepoint: First visit, one and two weeks after treatment. Method of measurement: With Reids colposcopic index: cervical intraepithelial neoplasia 1, 2, 3. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRahil Askari Nejad Behzadi
Fatemieh Hospital
Outcome results
None listed