Condition 1: Obsessive-Compulsive Disorder. Condition 2: Cognitive performance. Obsessive-compulsive disorder Diseases of the nervous system
Conditions
Interventions
Deep brain stimulation (DBS), a neurosurgical procedure involving the implantation of a medical device called a neurostimulator, which sends electrical impulses, through implanted electrodes, to speci
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age: 16-65 Diagnosis and Severity: Sever and chronic OCD for at least 5 years, Yale-Brown scale at least 25, Hamilton scale at least 17, IQ more than 85 Treatment refractoriness: Not response for SSRI for 12 weeks, clomipramine 12 weeks, atypical antipsychotics for 6 weeks and CBT for 16 seasons
Exclusion criteria
Exclusion criteria: Psychotic disorders, bipolar disorder, autism disorder, substance abuse, epilepsy, dementia, Parkinson's disease and pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of OCD. Timepoint: every month. Method of measurement: Yale- Brown scale.;Neuropsychological performance. Timepoint: every month. Method of measurement: Neuropsychological tools. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects, such as headache, nausea and. Timepoint: during the intervention and 2 months after that. Method of measurement: questionnaire or observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza Arezoomandan
Iran University of Medical Sciences
Outcome results
None listed