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effect of platelet-rich plasma(PRP)on fertility in women with thin endometrium

effect of intrauterine infusion of autologous platelet-rich plasma(PRP)on endometrial thickness and pregnancy rate as secondary endpoint in FET cycles.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016102510210N6
Enrollment
100
Registered
2016-10-30
Start date
2016-09-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

noninflammatory disorder of female genital tract. Complication associated with artificial fertilization ,unspecified

Interventions

Intervention 1: Control group: Continue estradiol since day 2 of cycle till end of study. Intervention 2: - Intrauterine infusion of 0.5 cc of platelet rich plasma( PRP)that contained platelet 4-5 tim
Treatment - Drugs
Control group: Continue estradiol since day 2 of cycle till end of study
- Intrauterine infusion of 0.5 cc of platelet rich plasma( PRP)that contained platelet 4-5 times more than peripheral blood with uterine catheter is performed if endometrial thickness below 6 mm on da

Sponsors

Shiraz University Of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: All patient with infertility that refer to mother and child hospital due to embryo transfer and recently despite conventional treatment with low dose of estradiol(6 mg)in 10th day cycles have endometrial thickness less than 6 mm no have above factors or no agree of patients platelet dysfunction ,thrombocytopenia ,continue using NSAIDs in the recent 48 hours ,corticosteroids in the 1 mount before ,smoking ,recent fever, history of cancer ,Hb<,platelet<105000

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Endometrial thickness. Timepoint: in 10th day of cycles and 72 hr after infusion of PRP. Method of measurement: Trans vaginal sonography.

Secondary

MeasureTime frame
Clinical pregnancy or miscarriage. Timepoint: 4week after embryo transfer. Method of measurement: trans vaginal sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohadese Shirbani

Shiraz University Of Medical Science

shirbanim@gmail.com+98 71 3227 9715

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026