dry eye syndrome. Other disorders of lacrimal gland
Conditions
Interventions
Intervention 1: Intervention group: The first patient with a unique code (1) would be given package A (include tacrolimus 0.03% drop). Patients would instil tacrolimus 0.03% drop every 12 hours a day
Treatment - Drugs
Intervention group: The first patient with a unique code (1) would be given package A (include tacrolimus 0.03% drop). Patients would instil tacrolimus 0.03% drop every 12 hours a day for one month. P
Control group: The second patient with a unique code (2) would be given package B (include artificial tear drop). Patients would instil a drop of artificial tear drop, with trademark of Artelac, in ey
Sponsors
Vice Chancellor for research of Yazd University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients aged above 50 years old with cataract planned for phacoemulsification. Exclusion criteria: history of an ocular trauma or any chemical or thermal burn; allergy to any of the study medications; history of any condition that may cause dry eye; systemic connective tissue disease; corneal contact lens wear; any active ocular disease; uncontrolled systemic disease; a history of ocular allergic disease; prior refractive surgery or any ocular surgery; history of any medication which may induce dry eye; any history of inflammatory or infectious ocular disease; diagnosis of dry eye syndrome by Schirmer 1 test <10 mm or tear film break up time <10 seconds.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eye problems in doing daily jobs. Timepoint: Before intervention and one month after treatment. Method of measurement: Ocular Surface Disease Index questionnaire.;Tear break up time. Timepoint: Before intervention and one month after treatment. Method of measurement: In seconds, With timer and Slit Lamp.;Tear production. Timepoint: Before intervention and one month after treatment. Method of measurement: Schirmer 1 test in millimeters. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactArmin Hemati
Yazd University of Medical Sciences
Outcome results
None listed