herpetic non-necrotizing stormal keratitis. Herpesviral keratitis and keratoconjunctivitis
Conditions
Interventions
Intervention 1: Conventional treatment for Non- necrotizing herpetic stromal keratitis including (oral acyclovir 400 mg 5 times a day for 10 days and topical prednisolone acetate 1% eye drop every 2
Treatment - Drugs
Conventional treatment for Non- necrotizing herpetic stromal keratitis including (oral acyclovir 400 mg 5 times a day for 10 days and topical prednisolone acetate 1% eye drop every 2 hours with tape
In another group,beside conventional treatment with oral acyclovir(400mg, 5 times a day for 10 days) and topical prednisolone acetate 1% eye drop every 2 hours with tapering, topical tacrolimus eye dr
Sponsors
Guilan University of Medical Sciences, Pro-Vice -Chancellor for research
Eligibility
Sex/Gender
All
Age
10 Years to 90 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Cases with non-necrotizing herpetic stromal keratitis that are in active phase of disease. Exclusion criteria: Cases with necrotizing stromal keratitis or history of corneal graft, History of intraocular operation and trauma, Pregnant and breast feeding women will exclude for this study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in corneal opacity and edema. Timepoint: 3 days, one week, two weeks, three weeks and four weeks after treatment. Method of measurement: clinical exam and scoring. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in corneal vascularization. Timepoint: 3days,one week,two weeks,three weeks and four weeks after treatment. Method of measurement: clinical exam and scoring. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mitra Akbari
Guilan University of Medical Sciences
Outcome results
None listed