effect of propolis on oral mucositis resulting from radiotherapy

Evaluating and comparing the effect of systemic and local use of Propolis in oral mucositis resulting from radiotherapy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20161024030475N4

Enrollment

Registered

2019-07-21

Start date

2015-08-23

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral mucositis (ulcerative) due to radiation. Oral mucositis (ulcerative) due to radiation

Interventions

Intervention 1: Intervention group: local propolis and systemic placebo. Intervention 2: Intervention group: systemic propolis and local placebo. Intervention 3: Control group: local and systemic plac

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: head and neck cancer requiring radiotherapy mucositis

Exclusion criteria

Exclusion criteria: weak patients' cooperation allergic reaction to propolis

Design outcomes

Primary

Measure	Time frame
Mucositis severity and percentage. Timepoint: baseline / 2 weeks after completing radiotherapy. Method of measurement: based on WHO.;Incidence of mucositis. Timepoint: baseline. Method of measurement: starts 1-2 weeks after radiotherapy and is determined by clinical assessment.;TNF in saliva. Timepoint: baseline/ 2 weeks after completing radiotherapy. Method of measurement: ELISA Kis.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArayeh maleki

Tehran University of Medical Sciences

maleki.arayeh@gmail.com+98 21 8898 7667

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026