The effect of cefotaxime on improvement of pediatric dysentery

The comparison of cefotaxime and ceftriaxone on the duration of diarrhea in children with dysentery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016102211145N18

Enrollment

100

Registered

2017-01-08

Start date

2017-01-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dysentery. Gastroenteritis and colitis of unspecified origin

Interventions

Intervention 1: Intervention group: Intravenous infusion of cefotaxime 50 mg/kg every 8 hours. Intervention 2: Control group: Intravenous infusion of ceftriaxone 50 mg/kg daily.

Treatment - Drugs

Intervention group: Intravenous infusion of cefotaxime 50 mg/kg every 8 hours

Control group: Intravenous infusion of ceftriaxone 50 mg/kg daily

Eligibility

Sex/Gender

All

Age

2 Months to 14 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age of 2 months to 12 years; Having active stool exam Exclusion criteria: Severe malnutrition; Immune deficiency; Using of anti-diarrheal drugs

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

Measure	Time frame
Duration of hospital stay. Timepoint: At discharge. Method of measurement: Counting the days of hospitalization.	—

Primary

Measure	Time frame
Fever. Timepoint: Every 6 hours. Method of measurement: Mercury thermometer with axillary method.;Duration of bloody diarrhea. Timepoint: Daily. Method of measurement: Stool chart.;Duration of diarrhea. Timepoint: Daily. Method of measurement: Stool chart.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Reza Sharif

Kashan University of Medical Sciences

mrsharifmd@yahoo.com+98 31 5554 0026

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026