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Effect of Anthum graveolen on vulvovaginal Candidiasis

Effect of 2% dill (Anethum graveolens L.) vaginal suppositories and clotimazole 100 vaginal suppositories for the treatment of vulvovaginal Candidiasis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016101828789N4
Enrollment
60
Registered
2017-03-01
Start date
2015-11-11
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vulvovaginal Candidiasis. Candidiasis of vulva and vagina

Interventions

Intervention 1: one clotrimazole 100 mg vaginal Tablet every night for 7 nights. Intervention 2: one 2% dill (Anethum graveolens L.) vaginal suppositories every night for 7 nights.
Treatment - Drugs
one clotrimazole 100 mg vaginal Tablet every night for 7 nights.
one 2% dill (Anethum graveolens L.) vaginal suppositories every night for 7 nights

Sponsors

Mashhad University of Medical Sciences, Vice chancellor for research
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
17 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria consisted of married women aged 15- 49 years; have received a clinical diagnosis of vaginal candidiasis; have had a positive culture for vaginal candidiasis. Exclusion criteria: were pregnancy or breast-feeding; received antibiotic drugs and topical and systemic anti-fungal drugs within one month before; had three or more episode of VVC per year; missed more than one suppositories or vaginal tablet uses within seven consecutive days; had hypersensitivity to clotrimazole or Anthum graveolen.

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

MeasureTime frame
Improve Of Vulvovaginal Candidiasis. Timepoint: before intervention and7 days after intervention. Method of measurement: Microscopic evaluation.

Primary

MeasureTime frame
Itching. Timepoint: before intervention and 7 days after intervention. Method of measurement: 4-point likert-type scale.;Burning. Timepoint: before intervention and 7 days after intervention. Method of measurement: 4-point likert-type scale.;Vaginal discharge. Timepoint: before intervention and 7 days after intervention. Method of measurement: 4-point likert-type scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Tafaghodi

Mashhad University of Medical Sciences

Tafaghodim@mums.ac.ir+98 513843784

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026