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Effects of GnRH agonist for luteal support on improvement of intracytoplasmic sperm injection cycles

Effects of GnRH agonist for luteal support on improvement of intracytoplasmic sperm injection cycles: clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016101729027N2
Enrollment
240
Registered
2016-10-24
Start date
2016-04-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Noninflammatory disorders of female genital tract. Complication associated with artificial fertilization, unspecified

Interventions

Intervention 1: Intervention group: Subcutaneous injection of Triptorelin (0.1 mg) 6 days after ICSI. Intervention 2: Control group: Subcutaneous injection of placebo 6 days after ICSI.
Treatment - Drugs
Placebo
Intervention group: Subcutaneous injection of Triptorelin (0.1 mg) 6 days after ICSI
Control group: Subcutaneous injection of placebo 6 days after ICSI

Sponsors

Vice Chancellor for research of Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 38 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age between 20-38; Body mass index (BMI) between 20-30; fresh embryo transfer cycles; 3rd menstrual day serum FSH below 10; absence of low ovarian response according Bologna Criteria Exclusion criteria: unwillingness to continue; absence of good quality embryo; ovarian hyper stimulation (more than 18 mature follicle during ovarian stimulation)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy. Timepoint: 4 weeks after embryo transfer. Method of measurement: Transvaginal ultrasound.;Chemical pregnancy. Timepoint: 2 weeks after embryo transfer. Method of measurement: Serum BHCG.

Secondary

MeasureTime frame
Ongoing pregnancy. Timepoint: 10 weeks after embryo transfer. Method of measurement: Fetal heart beat in ultrasound.;Abortion. Timepoint: Before 20 weeks of pregnancy. Method of measurement: Fetal demise before 20 weeks of gestation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeila Nazari

Shahid Beheshti University of Medical Sciences

nazari@sbmu.ac.ir+98 21 2243 2558

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026