effect of drug. Unspecified adverse effect of drug or medicament
Conditions
Interventions
Intervention 1: 15 minutes before time of induction, Daxmedetomidine 0.6mic / kg / h and remifentanil 1mic/Kg/min are infused, at the time of induction Propofol 1-2.5 mg/Kg and neuromuscular blocking
Prevention
15 minutes before time of induction, Daxmedetomidine 0.6mic / kg / h and remifentanil 1mic/Kg/min are infused, at the time of induction Propofol 1-2.5 mg/Kg and neuromuscular blocking drug (Cisatracur
15 minutes before time of induction, Remifentanil 1mic/Kg/min is infused, at the time of induction Propofol 1-2.5 mg/Kg and neuromuscular blocking drug (Cisatracurium) 0.15 mg/Kg are injected and pati
Sponsors
Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients undergoing spine surgery and spinal referring to Imam Reza Kermanshah American Society of Anesthesiologists class (I-II). Exclusion criteria: patients with a history of severe systemic disease; body mass index greater than 30; patients with a history of high blood pressure (Blood Pressure greater than 140/90); severe respiratory diseases does not control; symptomatic heart disease; diabetic patients; consumers beta-blocker drugs; drug-addicted patients; patients with more than one laryngoscopy; the extreme sensitivity to drugs personality disorder; patients with more than 750 cc of blood during surgery.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood Pressure. Timepoint: 15 minutes before induction, intubation time, two minutes afte intubation, time of change position, and two minutes after the change of position, intraoperative period in minutes of 15,30,45,90, time of repositioning, two minutes after switching position. and before extubation, two, thirty and sixty minutes after extubation. Method of measurement: in mmHg using mercuric manometer.;Heart Rate. Timepoint: 15 minutes before induction, intubation time, two minutes afte intubation, time of change position, and two minutes after the change of position, intraoperative period in minutes of 15,30,45,90, time of repositioning, two minutes after switching position. and before extubation, two, thirty and sixty minutes after extubation. Method of measurement: number of heart rate in one minute. | — |
Secondary
| Measure | Time frame |
|---|---|
| Shivering. Timepoint: Postoperative. Method of measurement: Standard questionnaire.;Nausea. Timepoint: Postoperative. Method of measurement: VAS.;Vomiting. Timepoint: Postoperative. Method of measurement: VAS. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Javad Moradi
Kermanshah University of Medical Sciences
Outcome results
None listed