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Effects of barberry consumption on liver function and antioxidant capacity

Effects of daily consumption of barberry juice on the status of liver tests and markers of oxidative stress in healthy people

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016101517756N9
Enrollment
20
Registered
2016-10-31
Start date
2016-11-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver disease. Toxic liver disease

Interventions

Intervention: A full glass of barberry syrup (240 cc, equivalent to 1.74g/240 ml gallic acid and 0.745 g/240 ml berberine phenolic compounds) used on a daily basis for 2 weeks.
Treatment - Drugs
Intervention: A full glass of barberry syrup (240 cc, equivalent to 1.74g/240 ml gallic acid and 0.745 g/240 ml berberine phenolic compounds) used on a daily basis for 2 weeks

Sponsors

Vice Chancellery for Research of Birjand University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: university employee, age between 20 and 40, lack of a specific disease or use of antibiotics since two weeks from the study onset, non-use of alcohol or smoking, provision of informed consent; Exclusion criteria: suffering from a disease during the study, consumption of antibiotics and/or alcohol, or smoking during the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Antioxidant level. Timepoint: Before, 7 dats and 14 days after intervention. Method of measurement: Ferric Reducing Ability of Plasma (FRAP), Thiobarbituric acid reactive substances (TBARS).;Liver enzymes. Timepoint: Before, 7 dats and 14 days after intervention. Method of measurement: ALT, AST, ALK and bilirubin tests.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohadeseh Abolhasannezhad

Birjand University of Medical Sciences

m_abolhasannezhad@yahoo.com+98 56 3239 5680

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026