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Comparison the effect of propofol and ketamine on the incidence of emergence cough

Comparison the effect of propofol and ketamine on the incidence of emergence cough in children undergoing Tonsillectomy.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016101411662N11
Enrollment
80
Registered
2017-08-20
Start date
2017-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cough following tonsillectomy. Pain in throat

Interventions

Intervention 1: After spontaneous respiratory will be returned, patients in the 1st group received intravenous propofol. Intervention 2: In the second group after spontaneous respiration will be retur
Treatment - Drugs
After spontaneous respiratory will be returned, patients in the 1st group received intravenous propofol.
In the second group after spontaneous respiration will be returned, patients will be received intravenous ketamin.

Sponsors

Vice-Chancellery of Research and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 12 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria: All patients whom will be candidate for Tonsillectomy, Age 3 to 12 years. The exclusion criteria: Patients are not in ASA class I and II; The patients has abnormalities in face or upper airway such as (maxillofacial fractures, tumors); Patients with respiratory problems like asthma; Allergic patients, those who have behavioral problems that needs to use sedative drugs before entering the operating room; patients who have cough due to any cause before surgery and the patients refuse to enter the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Postoperative cough. Timepoint: 30 minutes -2- 4 -8 -12 -24 hours post operation. Method of measurement: Questioners: Number of postoperative cough will be registered.

Secondary

MeasureTime frame
Postoperative pain and agitation. Timepoint: 30 minutes,2, 4 ,8 ,12 and 24 hours post operation. Method of measurement: Questioners: CHEOPS and Richmond.;Nausea and Vomiting. Timepoint: 30 minutes,2, 4 ,8 ,12 and 24 hours post operation. Method of measurement: Questioners.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadAli Sahmeddini

Shiraz University Of Medical Sciences

sahmeddin@sums.ac.ir+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026