A comparison of the effect of morphine and tamsulosin with morphine alone in pain management of patients with renal stone

A comparison of the effect of morphine and tamsulosin with morphine alone in pain management of renal colic patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016101311956N9

Enrollment

200

Registered

2017-03-11

Start date

2016-10-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

renal colic. Unspecified renal colic

Interventions

Intervention 1: We administer morphine sulfate 0.1 mg/kg IV with oral tamsulosin 0.4 mg for the first group of patients. Intervention 2: We administer morphine sulfate 0.1 mg/kg IV with placebo for th

Treatment - Drugs

We administer morphine sulfate 0.1 mg/kg IV with oral tamsulosin 0.4 mg for the first group of patients.

We administer morphine sulfate 0.1 mg/kg IV with placebo for the second group of patients.

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients with renal colic; age between 18 to 55 years old. exclusion criteria: any history of opium addiction; pregnancy; any history of renal or hepatic disease; bilateral renal stones

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Before analgesic administration and 30 minutes , 2 , 4 and 6 hours after analgesic administration. Method of measurement: Visual analoge scale.	—

Secondary

Measure	Time frame
Headache. Timepoint: 30 minutes , 2 , 4 and 6 hours after analgesic administration. Method of measurement: Questionnaire.;Dizziness. Timepoint: 30 minutes , 2 , 4 and 6 hours after analgesic administration. Method of measurement: questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Aida Shams Hojati

Mashhad University of Medical Siences

shamsa931@mums.ac.ir+98 51 3762 3320

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026