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The therapeutic effect of intradermal injection of Measles, Mumps, and Rubella vaccine in treatment of palmoplantar warts in patients unresponsive to treatment

Clinical trial of effect of intradermal injection of MMR vaccine in treatment of Palmoplantar warts in patients unresponsive to treatment

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016101027636N3
Enrollment
60
Registered
2017-06-11
Start date
2015-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Viral warts. Viral warts

Interventions

Intervention 1: For the intervention group 0.1 mL intralesional MMR vaccine made by Razi institute will be injected. Intervention 2: For the control group 0.3 mL intralesional normal saline will be in
Treatment - Drugs
Placebo
For the intervention group 0.1 mL intralesional MMR vaccine made by Razi institute will be injected
For the control group 0.3 mL intralesional normal saline will be injected.

Sponsors

Vice chancellor for Research of Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: All patients with Palmoplantar warts Exclusion criteria: Acute febrile disease; treatment of warts within last month; History of allergic reaction to MMR vaccine; asthma; history of allergic skin disease such as eczema and hives, meningitis, seizure, primary or iatrogenic immunodeficiency; pregnancy; lactation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Wart size. Timepoint: 0-2-4-6-8-10 Weeks. Method of measurement: Wart observation.;Number of warts. Timepoint: 0-2-4-6-8-10 Weeks. Method of measurement: Observation.;Size of other lesions. Timepoint: 0-2-4-6-8-10 Weeks. Method of measurement: Observation.

Secondary

MeasureTime frame
Injection pain. Timepoint: 0-2-4-6-8-10 weeks. Method of measurement: yes-no.;Recurrency. Timepoint: 0-1-2-3-4-5-6 months. Method of measurement: yes-no.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGhasem Ramatpour Rokni, MD

Mazandaran University of Medical Sciences

dr.rokni@yahoo.com+98 11 3304 4804

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 22, 2026