Insulin Resistance. Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Intervention 1: Intervention group: One tab of verapamil, 40 mg, twice a day, oral, for 8 weeks. Intervention 2: Placebo group: One tab of amlodipin, 5, mg, once a day, oral, for 8 weeks. Intervention
Treatment - Drugs
Intervention group: One tab of verapamil, 40 mg, twice a day, oral, for 8 weeks
Placebo group: One tab of amlodipin, 5, mg, once a day, oral, for 8 weeks
Control group: Without usage of any drugs for 8 weeks
Sponsors
Vice Chancellor for research of Arak University of Medical Sciences
Eligibility
Sex/Gender
All
Age
25 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Type two diabetes; systolic blood pressure greater than 140 and less than 160 or diastolic blood pressure greater than 90 mmHg; age between 25-75 years old; intake of any oral drugs of diabetes; HbA1c between 7-8.5% Exclusion criteria: Low blood pressure; heart and brain disease; pregnancy; lactation; plan to pregnancy; intake of insulin; drugs such as contraceptive or etrogen or testosterone during past three months; chronic disease such as lung, renal, liver or GI; HbA1c between 7-8.5%; systolic blood pressure greater than 160 mmHg
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The changes of insulin resistance. Timepoint: The beginning of the study, After 8 weeks. Method of measurement: Blood examination test.;The changes of fasting blood sugar. Timepoint: The beginning of the study, After 8 weeks. Method of measurement: Blood examination test. | — |
Secondary
| Measure | Time frame |
|---|---|
| The changes of blood pressure. Timepoint: The beginning of the study, After 8 weeks. Method of measurement: Clinical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAfsaneh Talaei
Arak University of Medical Sciences
Outcome results
None listed