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Effect of Ginger (Zingiber Officinale) and Chamomile Mixed Sachet with Honey in The Treatment of Primary Dysmenorrhea

Comparison of the Efficacy of Ginger-Chamomile Mixed Sachet and Honey with Mefenamic Acid in The Treatment of Primary Dysmenorrhea and Associated Symptoms of Female Students that Living in the Arak University of Medical Sciences Dormitory: Randomized Controlled Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016100825031N5
Enrollment
280
Registered
2016-11-08
Start date
2016-10-22
Completion date
Unknown
Last updated
2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary dysmenorrhoea. Primary dysmenorrhoea

Interventions

Intervention 1: Group 1: sachet containing 1000 mg of ginger root powder and 5000 mg of chamomile with a teaspoonful of honey
3 time a day, from 2 day before the beginning of menstrual cycle until 5 day. Intervention 2: Group 2: sachet that contain 1000 mg of ginger root powder with a teaspoonful of honey
3 time a day, from 2 day before the beginning of menstrual cycle until 5 day. Intervention 3: Group 3: sachet that contain 5000 mg of chamomile with a teaspoonful of honey
3 time a day, from 2 day before the beginning of menstrual cycle until 5 day. Intervention 4: Group 4: 250 mg mefenamic acid capsule manufactured by Raha pharmaceutical company
3 time a day, from 2 day before the beginning of menstrual cycle until 5 day.

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Between 18 to 30 years old Unmarried The menstruation pain is started before 20 years old Regular menstrual cycles between 21 to 35 days Menstrual bleeding without passing clots Menstrual pain start a few hours before menstrual bleeding and to continue for 5 days Lack of chronic diseases Without peptic ulcer or duodenal ulcer Do not consume anticoagulant drugs Lack of burning, itching and abnormal vaginal discharge Without history of allergy to medicinal plants Lack of stress in the past two months Do not have to take medicine or special diet and smoking Without history of pelvic inflammatory disease Without history of gynecologic surgery Do not transfer or relocation during the next 6 months Do not have pain in all the time of menstrual bleeding Do not consume oral contraceptives Do not consume drugs class of benzodiazepines, barbiturates, narcotics and some antidepressants, such as fluoxetine Avoiding to use alcohol, aspirin, warfarin and heparin Without having specific diseases of liver, kidney and diagnosed depression

Exclusion criteria

Exclusion criteria: Patient's refusal to participate in the study Consume drugs irregularly The incidence of significant stress factors during the study The incidence of any disease that requires to consume drugs, nutritional supplements or vitamins for long-term Doing any type of surgery during the study Marriage or change location Do not fill out the questionnaire Unwillingness to continue consume their medication by patients Avoiding the consume of medication as a single dose

Design outcomes

Primary

MeasureTime frame
The severity of bleeding. Timepoint: Before intervention and after the first and third menstrual cycle. Method of measurement: (PBACs) Pictorial Blood Loss Assessment Chart.;Duration of bleeding. Timepoint: Before intervention and after the first and third menstrual cycle. Method of measurement: Measuring time.;The severity of pain. Timepoint: Before intervention and after the first and third menstrual cycle. Method of measurement: Visual analog scale.;Symptoms of dysmenorrhea. Timepoint: Before intervention and after the first and third menstrual cycle. Method of measurement: Verbal scale Anthresh - Mylsum.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Shabani

Arak University of Medical Sciences

f.shabani@arakmu.ac.ir+98 86 3417 3524

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026