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Comparison of the effect ofcasein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and Xylitol Chewing gums and probiotic yogurt on streptocuccos mutans and microbial dental plaque

Comparison of the effect of casein phosphopeptide-amorphous calcium phosphate(CPP-ACP) and Xylitol Chewing gums and probiotic yogurt on streptocuccos mutans and microbial dental plaque

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016100730193N1
Enrollment
112
Registered
2017-06-26
Start date
2017-01-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dental Plaque-Stereptocucos mutans counts. DENTAL EXAMINATION-Deposites on tooth

Interventions

Intervention 1: Intervention group 1: chewing 20 minutes Xylitol gum 3 times a day for 30 days. Intervention 2: Intervention group 2: chewing 20 minutes CPP-ACP gum 3 times a day for 30 days. Interve
Treatment - Drugs
Intervention group 1: chewing 20 minutes Xylitol gum 3 times a day for 30 days.
Intervention group 2: chewing 20 minutes CPP-ACP gum 3 times a day for 30 days
Intervention group 3:200 grams probiotic yogurt once a day for 30 days
Control group 4: 5 cc chlorhexidine mouth rinse every night for 15 days

Sponsors

Research Vice chancellor of Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 27 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Dental students; have 22 teeth; good oral hygiene Exclusion criteria: systemic diseases that affect dental and periodental conditions; orthodontic appliance; active dental caries; choronic mucosite; chronic antibiotic usage; antibacterial mouth rinse consumption; drugs consumption which affect saliva flow rate; radio therapy history

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Human smutans streptococci counts in salive-Dental Plaque. Timepoint: base line -15 day-30 day. Method of measurement: Micobial culture-plaque index.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Iman Parisay

Mashhad Dental Faculty

parisayi@mums.ac.ir+98 51 3882 9501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026