The effect of melatonin on patients with hemorrhagic stroke

The benefit of Melatonin on damage associated molecular pattern following hemorrhagic strokepatients under mechanical ventilation

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016100530164N1

Enrollment

Registered

2017-03-04

Start date

2016-12-06

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nontraumatic intracranial haemorrhage. Intracranial haemorrhage (nontraumatic), unspecified

Interventions

Intervention 1: Melatonin tablet 30 mg every night for 5 days. Intervention 2: There is no intervention in control group.

Treatment - Drugs

Melatonin tablet 30 mg every night for 5 days

There is no intervention in control group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: inclusion criteria: patients with hemorrhagic stroke who have been admitted within 72 hours after stroke exclusion criteria: liver failure (liver enzymes more than 3 fold); renal failure (GFR<60); patients with brain tumor

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
S100B. Timepoint: Before intervention and 5 days after initiation of intervention. Method of measurement: Laboratory Kit.	—

Secondary

Measure	Time frame
GCS. Timepoint: Before the intervetion and 5 days after initiation of intervention. Method of measurement: GCS evaluating score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehrnoush Dianatkhah

Tehran university of medical sience

mehrnoush.dianatkhah@gmail.com+98 21 6412 2130

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026