gabapentine effect on post operative nausea and vomiting

Investigate prophylactic effect of Gabapantine on nausea and vomiting after excision and graft in patient with burn

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016100230072N2

Enrollment

116

Registered

2017-05-09

Start date

2016-08-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nausea and vomiting. -

Interventions

Intervention 1: Intervention Group: Oral administration of Gabapantin 600 mg 2hours before anesthesia. Intervention 2: Control Group: No drug.

Prevention

Intervention Group: Oral administration of Gabapantin 600 mg 2hours before anesthesia

Control Group: No drug

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age 18 to 60 years old; ASA I&II ;early surgical excision and graft in Burned patient Exclusion criteria: Addiction; smoker; alcoholic patient; use of antiemetic; anti acid; analgesic; anti depressant; ca Chanel blocker; renal and hepatic insufficiency; underlying disease leading to nausea and vomiting; pregnancy; lactating; allergy to gabapentin or opium and motion sickness

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Nausea. Timepoint: PACU (T0) 6 hr post surgery (T1) 12 hr post surgery (T2) 18 hr post surgery (T3) 24 hr post surgery (T4). Method of measurement: vas score.;Vomitting. Timepoint: PACU (T0) 6 hr post surgery (T1) 12 hr post surgery (T2) 18 hr post surgery (T3) 24 hr post surgery (T4). Method of measurement: frequency.	—

Secondary

Measure	Time frame
Pain. Timepoint: PACU (T0) 6 hr post surgery (T1) 12 hr post surgery (T2) 18 hr post surgery (T3) 24 hr post surgery (T4). Method of measurement: vas.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Siamak Rimaz

Guilan university of medical sciences

smkrimaz@yahool.com+98 13 1321 0343

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026