Effect of cyclosporin on dry eye treatment

Effect of topical cyclosporin A in patients with dry eye referring to Ophthalmology Clinic of Vali-Asr Hospital in Birjand

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016093030059N1

Enrollment

Registered

2016-11-17

Start date

2016-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry Eye. Other disorders of lacrimal gland

Interventions

Intervention 1: Intervention group: The right eyes are considered as the intervention group in which one drop of cyclosporine A eye drop will be used every 12 hours for 3 months. Intervention 2: Contr

Treatment - Drugs

Intervention group: The right eyes are considered as the intervention group in which one drop of cyclosporine A eye drop will be used every 12 hours for 3 months.

Control group: The left eyes are considered as the control group in which one drop of artificial eye drop will be used every 12 hours for 3 months. (It is noteworthy that that the same amount of drop

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: All visitors to the ophthalmology clinic of Valiasr Hospital of Birjand with clinical and paraclinical signs of dry eye; willingness to participate in the study; Non-occurrence of blindness in or conjunctivitis of one eye or both eyes; absence of foreign body in the eye; non-closure of the eye because of recent surgery, or non-occurrence of dry eye after trauma or burning; Exclusion criteria: unwillingness to continue the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Dry eyes. Timepoint: Before intervention, one week, one month, and three months after intervention. Method of measurement: Schirmer's test; SPEED scale.;Feeling of sand in the eyes. Timepoint: Before intervention, one week, one month, and three months after intervention. Method of measurement: Schirmer's test; SPEED scale.;Itching. Timepoint: Before intervention, one week, one month, and three months after intervention. Method of measurement: Schirmer's test; SPEED scale.;Pain and burning eyes. Timepoint: Before intervention, one week, one month, and three months after intervention. Method of measurement: Schirmer's test; SPEED scale.;Watery eye. Timepoint: Before intervention, one week, one month, and three months after intervention. Method of measurement: Schirmer's test; SPEED scale.;Eye fatigue. Timepoint: Before intervention, one week, one month, and three months after intervention. Method of measurement: Schirmer's test; SPEED scale.	—

Measure

Time frame

Dry eyes. Timepoint: Before intervention, one week, one month, and three months after intervention. Method of measurement: Schirmer's test; SPEED scale.;Feeling of sand in the eyes. Timepoint: Before intervention, one week, one month, and three months after intervention. Method of measurement: Schirmer's test; SPEED scale.;Itching. Timepoint: Before intervention, one week, one month, and three months after intervention. Method of measurement: Schirmer's test; SPEED scale.;Pain and burning eyes. Timepoint: Before intervention, one week, one month, and three months after intervention. Method of measurement: Schirmer's test; SPEED scale.;Watery eye. Timepoint: Before intervention, one week, one month, and three months after intervention. Method of measurement: Schirmer's test; SPEED scale.;Eye fatigue. Timepoint: Before intervention, one week, one month, and three months after intervention. Method of measurement: Schirmer's test; SPEED scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactShabnam Ghavamahmadi

Birjand University of Medical Sciences

sh.ghavamahmadi@bums.ac.ir+98 56 3239 5000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026